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Ion Channel Reader
ICR series combine atomic absorption spectroscopy (AAS) with a patented micro sampling technology to accurately measure ion movement in a cell-based assay format.
Measuring activity of voltage-gated and ligand-gated ion channels, co-transporters and pumps. high throughput solution to investigate a broad range of membrane proteins including electro neutral targets detect ion movements across membrane proteins through quantifying intracellular and extracellular ion concentrations of interest using AAS.
Since ion flux is a direct measure of channel activity, such assays are robust and less sensitive to disturbances, and data are very consistent and predictive of drug potency. Used as a primary screening application for ion channel drug research and development, or as a secondary screen for drug safety evaluation.
ICR8100:
Suitable for medium throughput screening, 3-4 samples can be analyzed per minute and 96/384 well plates can be used as sample containers. At the same time, the highly sensitive ICR8100 can detect as low as 0.05 ppm Rb+. Even if the detection dosage is as low as 50 uL, the detection sensitivity of ICR8100 is maintained.
ICR12000:
Suitable for high throughput drug library screening and processing requirements of ion channel targets. fully automated and equipped with a stacker and barcode scanner. At present, handling up to 60,000 sample wells per day.
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STANDARD ONE YEAR MANUFACTURER WARRANTY:
The manufacturer warrants this product to be free from defects in workmanship and materials, under normal use and conditions, for a period of one (1) year for the original invoice date. Shipping and handling fees are to be paid for by the customer. The manufacturer agrees, at its option during the warranty period, to repair and defect in material or workmanship or to furnish a repaired or refurbished product of equal value in exchange without charge (except for a fee for shipping, handling, packing, return postage, and insurance which will be incurred by the customer). Such repair or replacement is subject to verification of the defect or malfunction and proof of purchase as confirmed by showing the model number on original dated sales receipt.
This warranty does not include: Any condition resulting from other than ordinary residential wear or any use for which the product was not intended, such as use in rental or contract trade or commercial use Any condition resulting from incorrect or inadequate maintenance or care Damage resulting from misuse, abuse, negligence, accidents or shipping damage Dissatisfaction due to buyer’s remorse Normal wear and tear Damages incurred during transportation Damages incurred during assembly or maintenance Any used, previously displayed items
CONDITIONAL RETURN POLICIES
Nodesus provides charged return support to certain technical products or services where an "Accept Return" tag is attached; Operation costs such as Shipping and Handling, Re-instock, Re-furbishment, etc may incur.